Background: The serratus anterior plane block SAPB is a novel method that provides lateral chest wall analgesia. Each of these methods has been demonstrated to provide effective perioperative analgesia in thoracic surgery. The aim of this study was to compare the intraoperative hemodynamic and analgesic benefits of deep versus superficial SAPB during video-assisted thoracic surgery VATS lobectomy. We included patients who were 20 to 75 years of age and scheduled to undergo VATS lobectomy with American Society of Anesthesiologists physical status 1 or 2. The primary outcome was intraoperative remifentanil consumption. We also recorded intraoperative systolic blood pressure SBP , heart rate HR , emergence time, and doses of rescue drugs used to manage hemodynamic instability. Additionally, there were no significant differences between the 2 groups in SBP and HR at any time point, emergence time, or amount of rescue drugs used. Abstract Background: The serratus anterior plane block SAPB is a novel method that provides lateral chest wall analgesia. Substances Analgesics, Opioid Remifentanil.
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Background: Recent technological advances in miniaturisation have allowed for a confocal scanning microscope to be integrated into trans-endoscopic probes enabling endoscopists to collect in vivo virtual biopsies of the gastrointestinal mucosa during endoscopy. Aims: The aim of the present study was to assess prospectively the clinical applicability and predictive power of a probe-based confocal laser endomicroscopy for the in vivo diagnosis of colorectal neoplasia. Methods: Patients with evidence of colorectal superficial neoplasia at routine endoscopy, were included prospectively in this study. The images were interpreted as either neoplastic or not according to vascular and cellular changes. Results: A total of 32 lesions were identified in 20 consecutive patients. Histopathology diagnosis was of adenomas in 19 cases, hyperplastic polyps in 11 cases and adenocarcinoma in 2 cases. Conclusions: pCLE permits high-quality imaging, enabling prediction of intraepithelial neoplasia with a high level of accuracy. Published by Elsevier Ltd. All rights reserved. Abstract Background: Recent technological advances in miniaturisation have allowed for a confocal scanning microscope to be integrated into trans-endoscopic probes enabling endoscopists to collect in vivo virtual biopsies of the gastrointestinal mucosa during endoscopy.